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ANTI-MICROBIAL PEPTIDE KNOWN AS PAPILLOSIN |
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Principal Investigator: G. MITTA
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TECHNICAL DESCRIPTION
The present invention relates to a novel antimicrobial peptide called Papillosin, identified and purified from a marine invertebrate.
This invention describes an amino acid sequence as follows: GFWKKVGSAAWGGVKAAAKGAAVGGLNALAKHIQ (SEQ No.1), its derivatives, its fragments and a polypeptide, as well as transformed host organisms capable of producing the peptide such as micro-organism, animal cells and plant, and the anti-microbial composition containing the peptide. It has been shown that this molecule is essentially active against gram-positive and gram-negative bacteria. The interesting particularity of this molecule is it's mode of action: it does not permit the induction of resistance on the part of bacterial targets.
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