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METHODS FOR MAKING NEW DENDRITIC CHELATED COMPOUNDS, THEIR PHARMACEUTICAL INGENEERING AND THEIR USE IN MEDICAL IMAGING |
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Principal investigator : FELDER-FLESCH Delphine
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CONTEXT
Functional medical imaging is one of the
fundamental tools for the comprehension of neurodegenerative diseases. Imaging
contrast agents, either magnetic or scintigraphic, must be biocompatible,
display a low toxicity, a great stability, be efficient at low concentrations
and be targeted to specific organs or tissues. Combining all these requirements
is still a challenge. Moreover, the development of such engineered biochemical
tools is long and expensive, especially when it requires the synthesis of
custom molecules.
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