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BORONIC ACIDS AND DERIVATIVES FROM BORYLATION OF ARYL AND VINYL DERIVATIVES VIA Pd COUPLING WITH DIISOPROPYLAMINO BORANE |
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Principal Investigator: VAULTIER
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CONTEXT
Arylboronic acids
and esters are generally prepared by borylation of aromatic organomagnesium or
organolithium derivatives. These methods are expensive, require specific
conditions and are not general, which renders them rather unattractive. The aim
of the invention is to provide boranes, which can be used in particular in a
coupling reaction, that is to say a reaction for the borylation of various
derivatives, which can be prepared by a simple process, which exhibit
sufficient stability to be stored and which can be readily refunctionalized.
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