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BORONIC ACIDS AND DERIVATIVES FROM BORYLATION OF ARYL AND VINYL DERIVATIVES VIA Pd COUPLING WITH DIISOPROPYLAMINO BORANE
Principal Investigator: VAULTIER

 

CONTEXT

Arylboronic acids and esters are generally prepared by borylation of aromatic organomagnesium or organolithium derivatives. These methods are expensive, require specific conditions and are not general, which renders them rather unattractive. The aim of the invention is to provide boranes, which can be used in particular in a coupling reaction, that is to say a reaction for the borylation of various derivatives, which can be prepared by a simple process, which exhibit sufficient stability to be stored and which can be readily refunctionalized.


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