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FUNCTIONALIZED CARBON NANOTUBES, THEIR FABRICATION PROCESS AND THEIR USE IN NANOMEDICINE |
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Principal investigator : BIANCO Alberto
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TECHNICAL DESCRIPTION
The
present invention relates to the preparation of the functionalized carbon
nanotubes; and a pharmaceutical formulation comprising at least one of the
carbon nanotube in association with different type of therapeutic agents
including peptides, proteins, nucleic acids and small drugs.
The advantage of the
functionalized carbon nanotubes is that they have full-length functional
groups, hence enable linking various active molecules; are soluble in wide
range of organic and physiological solvents; are biocompatible; do not possess
intrinsic immunogenicity; and can penetrate into cells, thereby carrying the
covalently bound active molecules to cellular compartments. These nanotubes are
non-toxic and small, resulting in better penetration cells and in cell nuclei.
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