CONTEXT

Galanthamine is an alcaloide isolated from Amaryllidaceae acting as a competitive, selective and reversible inhibitor of acetylcholinesterase. This compound has been used for few years as it enhanced Alzheimer patients cognitive functions. Current methods of obtaining are either extraction from different type of Amaryllidaceae but only in low quantity or biomimetic or non biomimetic synthesis. These last methods are known to be expensive, long and not efficient. Therefore, as the market linked to the Galanthamine and its derivatives as well as analogues tends to increase, there is a demand nowadays for a cost-effective, fast and easy method.