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PLATINUM-BASED N-HETEROCYLIC CARBENIC COMPLEXES SHOWING VERY EFFICIENT ANTI-CANCER ACTIVITY |
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Stéphane Bellemin
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CONTEXT
Some platinum-based compounds are known to be efficient
anti-cancer drugs. Among these compounds, the cisplatin is one of the more
frequently used in the world. Nevertheless, this compound do have limitations:
its scope of activity is restricted, some cancer cells have or can develop a
resistance towards it, its side effects are numerous and its only method of
delivery is through intravenous as it doesn’t show good solubility in water.
Recently a new class of platinum-based compounds has
been monopolizing scientists’ attention for its efficient anti-cancer activity:
platinum-based N-heterocyclic carbenic complexes.
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