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PHOSPHOLE DERIVATIVES COMPLEXED WITH METALS AND PHARMACEUTICAL USES THEREOF |
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Principal Investigator: Elisabeth DAVIOUD-CHARVET
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TECHNICAL DESCRIPTION
This invention describes pharmaceutical compositions containing phosphole derivatives complexed with gold or platinium and their use in particular for the prevention or treatment of pathologies associated with an excess activity of human glutathione reductase and/or thioredoxin reductaseÀ. These components act as irreversible inhibitors of glutathione and thioredoxin reductases.
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