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INJECTABLE COMPOSITE CEMENT : CALCIUM-STRONTIUM PHOSPHATE/ PLAGA MICROPARTICLES LIKE OSSEOUS SUBSTIT
P. BOUDEVILLE, M. VERT and S. MUNIER

TECHNICAL DESCRIPTION

The present invention is an injectable hydraulic cement in particular made up of CaHPO4,2H2O, CaO and strontium carbonate, and composite material containing microparticles of a biodegradable polymer (PLAGA) as filler. Due to their composition, these two products are bioactive, bioresorbable and release strontium ions promoting osteogenesis.
They are radio opaque; this allows a follow-up of interventions of osseous fillings. They present a weak expansion during the setting which makeit possible to get a better contact cement-bone. They are finally prepared with commercial and cheap products.

Due to its excellent filling rate and setting rate, the cement is an perfect candidate for vertebroplasty.

The composite material can be also injected. The PLAGA microspheres, by fast degradation, give a structure with inter-connected macrospores enhancing the cement resorption and osseous rebuilding. Cause of its specific composition, this composite material present, due to the presence of the polymer before its degradation, good mechanical properties.


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