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BIODEGRADABLE AMPHIPHILIC COPOLYMERS FOR A SYSTEM OF VECTORISATION |
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Principal Investigator: Cédric CHAUVIERRE
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TECHNICAL DESCRIPTION
It also describes a method for synthesis of these copolymers and of colloidal particles made of these copolymers.
The preparation of the copolymers is simple and is performed under totally organic-free solvent conditions. Preparation occurs in water according to a single step process. This method is very flexible for the synthesis of compounds with surface active properties and with easily controlled characteristics.
The invention also describes polysaccharide-coated colloidal polymer nanoparticles with surface properties that can be easily modulated by the choice of the polysaccharides. These nanoparticles are of special interest for pharmaceutical applications for drug delivery or as vaccine delivery devices.
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