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ENHANCED ACETYL- AND BUTYRYL- CHOLINESTERASE INHIBITOR |
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Pincipal investigator : GUILLOU Catherine
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CONTEXT
Memory
troubles linked to Alzheimer disease are known to be associated with the loss
of the cerebral cholineric functions through a drop in acetycholine
neuromediator. Current symptomatic therapy aims at increasing the level of
acetycholine by inhibiting acetylcholinesterase, the enzyme responsible for
acetylcholine degradation. There is currently a demande for an efficient safe
inhibitor and esay to synthesize as most of current commercialized inhibitors
are hard to synthesize and have side effets.
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