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USE OF A DIPEPTIDE FOR THE OVERPRODUCTION OF TOXIC HYDROPHOBIC PEPTIDES IN BACTERIA |
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Principal Investigator: P. FALSON
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TECHNICAL DESCRIPTION
This invention describes a new expression system to supress the toxic effect of hydrophobic peptides in Procaryotes.
The expression system includes a plasmid characterized by 3 nucleotidic sequences running from 5' to 3' and coding successively for a soluble protein, an Asp-Pro dipeptide and a toxic protein.
The system allows the production of membrane domain of viral proteins (HCV, HIV...) or other toxic proteins.
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