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ORAL DELIVERY OF ACTIVE COMPOUNDS ENCAPSULATED IN SURFACE-MODIFIED POLYMERIC CAPSULES : application to Insulin and P140 delivery |
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Principal Investigator: Yves FRERE
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CONTEXT
To date, despite several leading studies aimed at orally administering coupounds sensitive to the conditions of the gastrointestinal tract (pH, mechanical stress, various enzymatic attacks), it has not been possible to satisfactorily combine the comfort and more physiological way of taking a medicament orally with the advantages of administration by injection (absence or small amount of denaturation or degradation of the active ingredient, rapid action in view of its instantaneous availability in the blood).
In an attempt to solve this problem, research team has developped a potential complex vector adpted to oral delivery of active ingredients.
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