CONTEXT

After antibiotics administration, a fraction of the drug is not absorbed and follows its progression to the colon before elimination. Intestinal excretion of residual and active antibiotics has various deleterious consequences:

•  Intestinal flora disturbance and perturbation of the resistance functions to  exogenous bacteria colonisation,
• Selection of resistant micro-organisms to administered antibiotics, whose dissemination can constitute a resistance mechanisms source, in a context of multiresistance development of various human pathogenic species.

Accidental or deliberate ingestion of medicines or domestic substances also represents a situation where adsorption or inactivation of undesirable molecules in the digestive tract is crucial.

Therefore, there is a real need for new galenic forms allowing elimination by adsorption or inactivation of undesirable molecules in the gastrointestinal tract, and overcoming disadvantages and obstacles of existing forms.