|
BIOCHIPS WITH TRANSISTOR BASED LABEL-FREE DETECTION |
|
Principal Investigator: U. Bockelmann
|
TECHNICAL DESCRIPTION
The invention relates to a method for detecting at least one parameter representative of molecular probes fixed to active zones (3) of a sensor, characterized in that said sensor comprises a network of field-effect transistors (T1, T2...) each of which has a source region (S), a drain region (D) and a gate region which form an active zone (3) on which said representative parameter may be detected, comprising the following steps: a) bringing some of said zones (3) into contact with molecular probes in order to fix the above, b) bathing at least those zones which have been brought into contact with a molecular probe in an electrolyte solution and c) measurement of at least one point of the characteristics drain current/drain-source voltage/gate-source voltage for at least two transistors of a first group, corresponding to zones (3), brought into contact with a molecular probe in order to infer at least one said parameter by comparison of at least two of said measurements obtained for two different zones (3).
To read more, please register or connect in the right pannel... |
