|
MONOCLONAL ANTIBODY TARGETING AURORA-A KINASE |
|
Principal Investigator: C. PRIGENT
|
TECHNICAL DESCRIPTION
The present invention is a monoclonal antibody which targets the mammal aurora-A kinase (human and mouse). As the overexpression of aurora-A kinase has been observed in many tumors, it is very important to assess its expression.
Mice were injected with human recombinant aurora-A kinase and then killed. Spleen cells were extracted and fused with immortalized hamster cells to obtain a hybridome. A hybridome has been isolated that produces an antibody with a high affinity for the aurora-A kinase.
To read more, please register or connect in the right pannel... |
